Lazoviz 1998.
Methods | Randomised trial, cross‐over design, data available prior to cross‐over. Study conducted in Institute for Obstetrics and Gynaecology, University of Belgrade, Belgrade, Yugoslavia Timing: not stated. |
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Participants | 56 participants randomised, 6 cycles/patient. Clomiphene‐resistant PCOS participants (high LH). Mean age, duration of infertility, infertility work‐up, mean BMI not stated | |
Interventions | Ovarian drilling with diathermy or laser vaporisation with CO2 (n = 28), versus Gonadotrophins (FSH or hMG) for ovulation induction for 6 cycles. Number of drill holes per ovary is not stated. (n = 28) Follow‐up for 6 months |
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Outcomes | Pregnancy rate (by participant), miscarriage rate (by pregnancy), multiple pregnancy rate (by pregnancy) | |
Notes | Conflict of interest: not stated | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No details in paper |
Allocation concealment (selection bias) | Unclear risk | No details in paper |
Blinding of participants and personnel (performance bias) All outcomes | High risk | No details of blinding, but unlikely to have occurred. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No details |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All participants appear to be included in the analysis |
Selective reporting (reporting bias) | High risk | This is a conference abstract only. No full paper was identified |
Other bias | High risk | Conference abstract |