Mehrabian 2012.

Methods	Parallel randomised controlled trial conducted in Obstetrics and Gynaecology clinic, Isfahan, Iran Timing: not stated
Participants	104 women randomised. Mean age of women in LOD group was 29.2 ± 5.5 years and in gonadotropin group was 28.5 ± 5.5 years Inclusion criteria: Nuliparous, aged < 40 years, clomiphene‐resistant, PCOS Exclusion criteria: Male‐factor or tubal‐factor infertility
Interventions	LOD: 10 to 15 punctures per ovary depending on size (n = 52), versus Gonadotropin: HMG given after the bleeding withdrawal and from day 3 of the cycle with 10 mg medroxyprogesterone (n = 52) Follow‐up: not stated
Outcomes	Pregnancy, miscarriage, ectopic pregnancy, OHSS, multiple pregnancy
Notes	Conflict of interest: not stated Clinical trial registration number: not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "computer ‐generated random numbers"
Allocation concealment (selection bias)	Unclear risk	No details
Blinding of participants and personnel (performance bias) All outcomes	High risk	No details, but unlikely due to different interventions
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No details
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women randomised were analysed
Selective reporting (reporting bias)	Unclear risk	We could not retrieve the original protocol. Prespecified outcomes appear to be reported
Other bias	Low risk	Groups balanced at baseline