Nasr 2015.
Methods | Parallel randomised controlled trial conducted in Women's Health Centre, Assiut University. Egypt Timing: Not stated |
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Participants | 80 women randomised. Mean age of women in adjusted group was 27.7 ± 2.1 years and in the fixed group was 28.5 ± 1.9 years Inclusion criteria: Clomiphene‐resistant PCOS Exclusion criteria: No details |
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Interventions | Adjusted thermal dose based on ovarian volume (n = 40), versus Fixed thermal dose 600 J per ovary through 4 punctures regardless of size (n = 40) A third group of normally‐ovulating women acted as controls but are not included in these analyses Follow‐up for 6 months |
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Outcomes | AMH levels, ovulation, conception (no details), early abortion rates | |
Notes | Conflict of interest: not stated Clinical trial registration number: not stated Conference abstract |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No details are provided of method used to generate the random sequence |
Allocation concealment (selection bias) | Unclear risk | No details are provided of the method used to conceal allocation to treatment groups |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No details provided of blinding of participants or trial personnel |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No details provided of blinding of outcome assessors |
Incomplete outcome data (attrition bias) All outcomes | High risk | No details provided of levels of attrition |
Selective reporting (reporting bias) | High risk | Only available as a conference abstract, no full publication available |
Other bias | High risk | Conference abstract only |