Rimington 1997.
| Methods | Randomised prospective study conducted in a Fertility clinic in Wales, UK Timing: not stated |
|
| Participants | 50 women, mean age in IVF group was 31 (95% CI 29.8 to 32.2) and for LOE + IVF the mean age was 31.8 (95% CI 30.3 to 33.2) Inclusion: Diagnosis of PCOS, requiring IVF for reasons other than anovulation, at least 1 previous unsuccessful ovarian stimulation cycle with gonadotrophins Exclusion: Aged > 40 years, history of > 2 miscarriages, severe male‐factor infertility |
|
| Interventions | IVF (n = 25), versus Ovarian electrocautery and IVF (grid of holes 10 mm apart) ovarian stimulation started 1 week after LOE (n = 25). Follow‐up for 1 cycle |
|
| Outcomes | Number of abandoned cycles, OHSS, pregnancy, miscarriage | |
| Notes | Conflict of interest: not stated | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Quote: "Blocked method of randomisation.." |
| Allocation concealment (selection bias) | Unclear risk | No details in paper |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | There was no evidence of blinding of researchers or participants |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No details provided |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | All women randomised appear to be analysed |
| Selective reporting (reporting bias) | Unclear risk | We could not retrieve the original protocol. All outcomes listed in the Methods section were reported in the Results |
| Other bias | Low risk | No evidence of other risk of bias |