Sorouri 2015.
| Methods | Parallel randomised controlled trial. Single centre in Fertility clinic, Al‐Zahara Hospital, Iran Timing: June 2011 to July 2012. |
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| Participants | 100 women randomised. Mean age of women in the unilateral group was 27.6 ± 4.3 years and in bilateral group was 28.0 ± 4.3 years Inclusion criteria: Women with PCOS (Rotterdam 2003 criteria) and clomiphene resistance Exclusion criteria: Tubal disease, peritoneal adhesions to tubes or ovaries, endometriosis, endocrine abnormality, concomitant male infertility. |
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| Interventions | Unilateral ovarian drilling (right ovary) (n = 50), versus Bilateral ovarian drilling (n = 50) Unipolar diathermy needle, 8 mm, 60 W and 5 points per ovary Follow‐up for 6 months |
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| Outcomes | Menstrual calender, serum LH and FSH, ovulation, clinical pregnancy | |
| Notes | No conflict of interest Funding from Guilan University of Medical Sciences Clinical trial registration number: not stated |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Blocked sample randomisation, no other details |
| Allocation concealment (selection bias) | Unclear risk | No details provided |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Surgeons were blinded |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No details provided |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 45 women in each group were analysed. In the unilateral group 2 women were excluded with tubal disease found during laparoscopy and 3 missed follow‐up visit. In the bilateral group, 1 woman was excluded because of endometriosis found during laparoscopy and 4 were excluded as they missed follow‐up visits |
| Selective reporting (reporting bias) | Low risk | We found the registered protocol on irct.ir (IRCT138903291306N2). All the outcomes mentioned in the protocol were presented in the published report |
| Other bias | Low risk | Groups balanced at baseline |