Youssef 2007.

Methods	Randomised trial conducted in Egypt Timing: January 2003 to December 20
Participants	87 women with PCOS. Mean age of unilateral group was 31.1 ± 4.2, and for the bilateral group was 29.8 ± 3.7 years Inclusion: infertility secondary to anovulation, unsuccessful treatment with clomiphene citrate and gonadotrophins
Interventions	Weight reduction and insulin sensitising drugs were tried first for 3 months Clomiphene citrate 50 mg daily for 5 days from day 3 to 7. If no response then increased up to 150 mg daily for 5 days. If still no response HMG used to stimulate ovulation Unilateral LOD: If both ovaries equal size the right one was drilled, if of unequal size then the larger one was treated (n = 43), versus Bilateral LOD (n = 44). Ovaries were cauterised at 4 points Follow‐up for 1 year
Outcomes	Postoperative pain, postoperative nausea, ovulation, pregnancy, miscarriage
Notes	Conflict of interest: not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No details provided in paper
Allocation concealment (selection bias)	Low risk	Quote: "randomly allocated by an independent investigator blinded to the treatment group...using the closed envelope method"
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No details provided
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Outcome assessors were blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	All women appear to have been followed up and analysed
Selective reporting (reporting bias)	Unclear risk	We could not retrieve the original protocol. All outcomes listed in the Methods section were reported in the Results
Other bias	Low risk	No evidence of other risk of bias