NCT02239107.

Trial name or title	N‐acetyl cysteine for ovulation induction in clomiphene citrate‐resistant polycystic ovary syndrome
Methods	Randomised controlled trial, parallel‐assignment
Participants	Inclusion criteria: 18 to 39 years; PCOS women according to Rotterdam criteria who failed to respond to 6 months ovulation induction therapy with clomiphene citrate; normal semen analysis of partner; normal tubo‐peritoneal anatomy as assessed by laparoscopy Exclusion Criteria: Other causes of infertility; receiving gonadotrophin ovulation induction
Interventions	LOD versus LOD plus N‐Acetyl cysteine 1200 mg daily in 2 divided doses starting on cycle day 2 for 6 months
Outcomes	Primary outcome measures: ovulation rate Secondary outcome measures: pregnancy rate
Starting date	January 2012
Contact information	Esraa Yousef Badran, Egypt
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