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. 2020 Feb;190(2):426–441. doi: 10.1016/j.ajpath.2019.10.014

Figure 6.

Figure 6

Airway structure and morphology is altered in the absence of COL6. A: Representative images of whole transverse sections of the left lung from wild-type (WT) and Col6a1−/− mouse lungs. B: Quantification of average airway number per section in WT and Col6a1−/− mice. C: Representative images of airways from two different WT and Col6a1−/− mouse lungs. DF: Quantification of airway epithelial cell density (nuclei/100 μm; D), airway mucosal thickness (E), and average distance between airway epithelial cell nuclei and basement membrane (F) in WT and Col6a1−/− mice. n = 9 WT and Col6a1−/− mice (B); n = 6 WT mice (DF); n = 7 Col6a1−/− mice (DF). **P < 0.01, ***P < 0.001 versus WT. Scale bars: 1 mm (A); 100 μm (C).