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Medroxyprogesterone acetate (MPA) prevents the onset of cervical cancer. A: Treatment regimens for the chemopreventive approach are depicted. All mice were treated with E2 (estrogen) until end points (3, 4, or 6 months). Arrowheads indicate monthly injections with MPA. B: MPA induces hypoplasia in the cervix. Shown are high-magnification images of representative hematoxylin and eosin–stained cervical tissues. Scale bar = 50 μm.
