Table 2.
Comparison of demographic features and treatment outcomes between benign and malignant lacrimal sac tumors.
| Benign (n = 46) | Malignant (n = 19) | p value | |
|---|---|---|---|
| Gender | |||
| Male | 19 | 11 | 0.22 |
| Female | 27 | 8 | |
| Mean onset age (years) | 60.2 ± 15.2 | 48 ± 9.3 | 0.03∗ |
| Mass extending above the medial canthal tendon | 4/46 (9%) | 14/19 (74%) | <0.001∗ |
| CT imaging∗∗ | |||
| Bone erosion | 1/9 (11%) | 8/16 (50%) | <0.05∗ |
| Infiltrative lesion | 0/9 (0%) | 10/16 (63%) | <0.05∗ |
| Treatment | |||
| Surgical resection | 38 | 19 | |
| Adjuvant RT | 8 | ||
| Adjuvant CCRT | 9 | ||
| Local recurrence rate | 3/46 (6%) | 8/19 (42%) | 0.001∗ |
| Metastatic rate | 0 | 9/19 (47%) | |
| Mortality rate | 0 | 10/19 (53%) | |
| Mean follow-up time (months) | 48.9 (0.25–128) | 76.2 (3–168) | |
Values are presented as n (%), mean ± SD or mean (range). CT, computed tomography; RT, radiotherapy; CCRT, concurrent chemoradiotherapy. ∗p < 0.05. ∗∗CT imaging data were available on 9 patients with benign lesions and 16 patients with malignant lesions.