Table 1.
Sequencing reads of the plasma DNA from the 11 inborn errors of metabolism patients underwent liver transplantation.
| Case | Sex | Donor | Sex-mismatched | Time-pointa | Reads aligned to chromosome Y |
Reads in all chromosomes |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | 105-145bp | >145bp | Total | 105∼145bp | >145bp | |||||
| 1 | M | Mother | Y | d0 | 9108 | 1604 | 6981 | 7,153,507 | 1,165,831 | 5,205,502 |
| M | Mother | Y | d1 | 1160 | 268 | 799 | 3,760,805 | 1,081,429 | 2,147,428 | |
| M | Mother | Y | d7 | 1797 | 406 | 1075 | 4,177,477 | 998,579 | 2,618,310 | |
| M | Mother | Y | d14 | 7105 | 653 | 6136 | 6,102,624 | 601,390 | 4,980,364 | |
| M | Mother | Y | d30 | 7186 | 798 | 5991 | 6,212,544 | 697,034 | 4,871,012 | |
| M | Mother | Y | d60 | 6305 | 822 | 5050 | 5,437,920 | 683,801 | 4,112,475 | |
| 2 | F | Father | Y | d0 | NA | NA | NA | NA | NA | NA |
| F | Father | Y | d1 | 6763 | 1894 | 4375 | 3,557,290 | 1,341,454 | 3,013,608 | |
| F | Father | Y | d7 | 3884 | 699 | 2890 | 4,866,068 | 1,173,209 | 3,078,763 | |
| F | Father | Y | d14 | 1751 | 245 | 1408 | 3,388,331 | 765,763 | 4,128,225 | |
| F | Father | Y | d30 | 346 | 49 | 259 | 3,813,946 | 763,552 | 3,747,196 | |
| F | Father | Y | d60 | 200 | 36 | 138 | 4,396,055 | 830,857 | 4,016,866 | |
| 3 | M | Father | N | d0 | 5382 | 790 | 4209 | 4,387,036 | 598,479 | 3,251,571 |
| M | Father | N | d1 | 5651 | 1508 | 3705 | 4,622,284 | 1,073,034 | 2,924,354 | |
| M | Father | N | d7 | 5443 | 858 | 4157 | 4,660,322 | 668,456 | 3,348,575 | |
| M | Father | N | d14 | 4758 | 644 | 3925 | 3,953,748 | 486,804 | 3,153,691 | |
| M | Father | N | d30 | 5918 | 754 | 4811 | 5,030,687 | 603,692 | 3,894,321 | |
| M | Father | N | d60 | 7138 | 994 | 5645 | 6,064,013 | 802,309 | 4,442,660 | |
| 4 | F | Mother | N | d0 | 93 | 23 | 56 | 5,382,863 | 767,323 | 3,950,037 |
| F | Mother | N | d1 | 101 | 29 | 48 | 5,584,612 | 1,404,413 | 3,319,138 | |
| F | Mother | N | d7 | 72 | 7 | 46 | 4,354,163 | 920,217 | 2,787,415 | |
| F | Mother | N | d14 | 82 | 10 | 63 | 5,599,003 | 796,692 | 4,285,613 | |
| F | Mother | N | d30 | 107 | 14 | 69 | 5,720,462 | 687,978 | 4,528,933 | |
| F | Mother | N | d60 | 86 | 14 | 52 | 4,636,331 | 565,747 | 3,675,836 | |
| 5 | F | Father | Y | d0 | 124 | 19 | 89 | 6,023,962 | 847,282 | 4,437,286 |
| F | Father | Y | d1 | 5166 | 1380 | 3415 | 6,470,979 | 1,455,386 | 4,124,304 | |
| F | Father | Y | d7 | 2946 | 488 | 2235 | 5,435,357 | 1,266,813 | 3,259,309 | |
| F | Father | Y | d14 | 1866 | 241 | 1518 | 5,819,452 | 706,961 | 4,549,664 | |
| F | Father | Y | d30 | 255 | 35 | 187 | 6,717,742 | 764,961 | 5,196,170 | |
| F | Father | Y | d60 | 281 | 50 | 192 | 6,477,861 | 789,161 | 5,026,852 | |
| 6 | M | Mother | Y | d0 | 4626 | 556 | 3752 | 3,761,858 | 468,708 | 2,831,986 |
| M | Mother | Y | d1 | 1929 | 295 | 1468 | 4,354,163 | 920,217 | 2,787,415 | |
| M | Mother | Y | d7 | 4413 | 718 | 3297 | 4,824,852 | 812,866 | 3,441,641 | |
| M | Mother | Y | d14 | 5534 | 621 | 4668 | 5,176,431 | 573,489 | 4,145,069 | |
| M | Mother | Y | d30 | 4947 | 672 | 4008 | 4,462,548 | 568,024 | 3,464,896 | |
| M | Mother | Y | d60 | 5878 | 778 | 4705 | 5,295,286 | 694,273 | 3,968,044 | |
| 7 | F | Mother | N | d0 | 62 | 7 | 39 | 3,305,870 | 464,613 | 2,418,256 |
| F | Mother | N | d1 | 84 | 16 | 54 | 5,644,858 | 1,012,010 | 3,832,261 | |
| F | Mother | N | d7 | 78 | 10 | 46 | 1,637,625 | 226,575 | 1,205,254 | |
| F | Mother | N | d14 | 124 | 11 | 97 | 5,752,959 | 666,542 | 4,531,273 | |
| F | Mother | N | d30 | 71 | 12 | 50 | 5,078,241 | 610,475 | 4,008,862 | |
| F | Mother | N | d60 | 93 | 15 | 59 | 5,625,564 | 691,607 | 4,394,909 | |
| 8 | M | Mother | Y | d0 | 5523 | 661 | 4449 | 4,613,560 | 547,227 | 3,498,275 |
| M | Mother | Y | d1 | 3796 | 854 | 2502 | 5,565,320 | 1,435,290 | 3,226,249 | |
| M | Mother | Y | d7 | 4986 | 626 | 3945 | 5,322,285 | 1,025,954 | 3,620,193 | |
| M | Mother | Y | d14 | 6149 | 694 | 5095 | 5,550,906 | 635,790 | 4,378,132 | |
| M | Mother | Y | d30 | 7337 | 796 | 6161 | 6,360,163 | 716,026 | 4,988,342 | |
| M | Mother | Y | d60 | 7469 | 1134 | 5812 | 6,533,085 | 907,020 | 4,770,280 | |
| 9 | M | Mother | Y | d0 | 7467 | 791 | 6156 | 5,889,870 | 643,756 | 4,515,185 |
| M | Mother | Y | d1 | 2990 | 711 | 1968 | 5,435,357 | 1,266,813 | 3,259,309 | |
| M | Mother | Y | d7 | 4894 | 801 | 3773 | 5,999,806 | 1,005,095 | 4,411,994 | |
| M | Mother | Y | d14 | 5705 | 661 | 4770 | 5,122,931 | 584,550 | 4,092,357 | |
| M | Mother | Y | d30 | 6088 | 688 | 5073 | 4,783,192 | 541,566 | 3,815,172 | |
| M | Mother | Y | d60 | 7945 | 1059 | 6336 | 6,923,195 | 914,019 | 5,137,872 | |
| 10 | M | Mother | Y | d0 | 7224 | 844 | 5882 | 5,567,996 | 684,041 | 4,196,801 |
| M | Mother | Y | d1 | 1438 | 357 | 970 | 4,177,477 | 998,579 | 2,618,310 | |
| M | Mother | Y | d7 | 6117 | 697 | 5141 | 5,492,685 | 651,822 | 4,369,007 | |
| M | Mother | Y | d14 | 6517 | 749 | 5433 | 5,218,482 | 600,041 | 4,111,675 | |
| M | Mother | Y | d30 | 5560 | 641 | 4594 | 4,743,502 | 587,815 | 3,654,160 | |
| M | Mother | Y | d60 | 7571 | 960 | 6017 | 7,094,356 | 923,938 | 5,205,815 | |
| 11 | M | Father | N | d0 | 5840 | 855 | 4556 | 4,714,376 | 692,469 | 3,416,575 |
| M | Father | N | d1 | 6688 | 1423 | 4764 | 5,322,285 | 1,025,954 | 3,620,193 | |
| M | Father | N | d7 | 7048 | 1236 | 5317 | 5,590,017 | 925,345 | 4,071,872 | |
| M | Father | N | d14 | 7867 | 758 | 6721 | 6,097,298 | 605,475 | 4,902,337 | |
| M | Father | N | d30 | 7554 | 1051 | 6080 | 6,102,619 | 840,679 | 4,621,985 | |
| M | Father | N | d60 | 7763 | 1002 | 6253 | 6,335,392 | 782,798 | 4,843,640 | |
d0 = operation day, sampling before operation; d1 = 1 day after operation; d7 = 7 days after operation; d14 = 14 days after operation; d30 = 30 days after operation; d60 = 60 days after operation.