Table 4.
Optical Coherence Tomography Findings in the GUCY2D Cohort
| Patient | VA (OD/OS) | Age at Baseline OCT (Y) | Follow-up Time (Y) |
OCT EZ Appearance at Both Baseline and Follow-up |
|---|---|---|---|---|
| P1 | 1.3/1.2 | 47.3 | 6.2 | Continuous/intact EZ |
| P2A | 1.8/1.5 | 59.6 | 4.2 | Focally disrupted with RPE changes |
| P2B | HM | 54.8 | 4.2 | Focally disrupted with RPE changes |
| P3 | 1.3/1 | 47.4 | 13.3 | Diffuse EZ/RPE change |
| P4 | 0.48/0.6 | 20.3 | 3.0 | Focally disrupted EZ |
| P5 | 0.48/0.62 | 8.0 | 4.0 | Continuous/intact EZ |
| P8A | HM | 25.4 | NA | Continuous/intact EZa |
| P9 | HM | 11.3 | 3.0 | Continuous/intact EZ |
| P13 | HM | 76.4 | 2.0 | Focally disrupted EZ |
| P14 | PL | 7.3 | 6.4 | Continuous/intact EZ |
| P19 | PL | 18.2 | NA | Continuous/intact EZa |
EZ = ellipsoid zone; HM = hand motions; OCT = optical coherence tomography; PL = perception of light; RPE = retinal pigment epithelium; VA = visual acuity.
a
No available follow-up OCT scan.