. 2020 Jan 15;21(2):559. doi: 10.3390/ijms21020559

Table 3.

Histological evaluation of organ toxicity after treatment with Cispt, LCispt, and PLCispt, and the serum concentrations of blood urea nitrogen (BUN), creatinine, alanine transaminase (ALT), alkaline phosphatase (ALP), and aspartate transaminase (AST) in these groups of animals.

Group	Number of Animals	Organ	Score	BUN (mg/dL)	Creatinine (mg/dL)	ALP (U/L)	ALT (U/L)	AST (U/L)
Cispt	10	Liver	2	67 ± 3.1	3.8 ± 0.2	273± 13.3	284 ± 14.3	365 ± 18.1
Cispt	10	Kidney	1–2	67 ± 3.1	3.8 ± 0.2	273± 13.3	284 ± 14.3	365 ± 18.1
LCispt	10	Liver	0–1	54 ± 2.6	3.1 ± 0.15	220± 11.1	237± 11.4	290± 14.3
LCispt	10	Kidney	1	54 ± 2.6	3.1 ± 0.15	220± 11.1	237± 11.4	290± 14.3
PLCispt	10	Liver	0–1	32 ± 1.5	1.8± 0.09	130± 6.2	138 ± 6.5	170± 8.2
PLCispt	10	Kidney	0–1	32 ± 1.5	1.8± 0.09	130± 6.2	138 ± 6.5	170± 8.2