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. 2020 Jan 14;21(2):526. doi: 10.3390/ijms21020526

Figure 10.

Figure 10

Time response to Isoproterenol (ISO, 10 µM, A); Isoproterenol (10 µM) + Matrix metalloproteinase inhibitor (MMPi-GM6001, 10 µM, B) and Isoproterenol (10 µM) + Eicosapentaenoic acid (EPA, 3.3 µM, C), recorded as spontaneously beating per 15 seconds of cultured neonatal rat cardiomyocytes. After the washing with pre-warmed SM20-I, the basal beating rate was estimated again after stimulation with fresh ISO. BR— beating rate; sec—seconds. Data are presented as means ± SEM; * p < 0.05 versus ISO 5´; # p < 0.05 versus 3xWasch.