Table 2.

Ratio of altered Genes in hallmarks.

Hallmarks	Num. of driven Mutation genes	Num. of driven Methylation genes	Num. of driven CNV genes	alteration genes/all driven genes	Ratio of altered Genes
AIM	1,098	334	1,003	1,098/1,101	99.73%
ERI	301	88	277	301/302	99.67%
EGS	617	234	491	645/678	95.13%
RCD	1147	349	1,025	1,147/1,150	99.74%
SPS	1261	356	1,160	1,261/1,263	99.84%
EID	583	258	506	583/591	98.65%
TPI	614	230	537	614/619	99.19%
GIM	220	73	187	220/221	99.55%
IA	482	198	427	482/483	99.79%
REM	438	95	402	438/440	99.55%

For each hallmark, the ratio of genes altered by mutation, methylation, and CNV were more than 95%.