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. 2020 Jan 9;21(2):435. doi: 10.3390/ijms21020435

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of ezrin mutations on the vimentin cytoskeleton. Box plots show the results of the total vimentin fiber intensity (A), fiber spread (B), location of the fiber peak (C), fiber thickness (D), fiber length (E), and fiber alignment (F). Box plots extend from the 10th to the 90th percentile, whiskers from the 5th to the 95th. A total of n = 585 (ezrin), n = 424 (ezrin T567D), n = 768 (ezrin T567A), and n = 425 (FERM) cells were analyzed from n = 6 repeats. Asterisks indicate a statistical difference (** p < 0.01, *** p < 0.001, obtained using Dunnett’s test against wild-type ezrin).