Table 2.

Amino acid mutation rates of the light and heavy chain genes of the anti-ZIKV_E scFv antibodies.

Region	FR1	FR2	FR3	FR4	Total FRs	CDR1	CDR2	CDR3	Total CDRs
VL	5–10%	6–19%	9–16%	0–9%	5–19%	50–88%	29–71%	36–64%	29–88%
VH	10–15%	0–7%	9–19%	0%	0–19%	20–100%	29–47%	63%	20–100%

FRs: Framework regions; CDRs: complementarity determining regions; VL: light chain of the variable region; VH: heavy chain of the variable region.