Figure 1.

Immunofluorescence of skin biopsies from patients affected by BCC. (A) TBX1 (green), E-cadherin, an epithelial cell marker (red), and 4′,6-diamidino-2-phenylindole (DAPI), which stains DNA (blue) showing the physiological expression of TBX1 in the hair follicle (HF, magnified in A′). (B) BCC connected to the epidermal layer: TBX1 is expressed in cancer cells (arrow, magnified in (B′) but not in healthy epidermis (arrowhead). SG: Sebaceous gland. Scale bar is 100 µm in (A,B), 50 µm in (A′,B′).