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The protein corona in cancer immunotherapy. Schematic description of an NP–PPC based therapy mechanism in which radiotherapy induces the release of tumor-derived protein antigens (TDPAs) that are integrated in the PC and promote the antigen presentation and the anti-cancer immune activation. This approach is applied in combination with checkpoint inhibitor therapy. Figure from [117]. PPC: personalized protein corona. AC-NPs refers to Antigen Capture-Nano Particles.
