H3K27M | Histone H3 Lysine 27 to Methionine Mutation |
DIPG | Diffuse Intrinsic Pontine Glioma |
DSBs | Double Strand Breaks |
CD | Calculated Dose |
XRT | Ionizing radiation treatment |
APR-246 | Mutant p53-reactivating agent |
GSK-J4 | Jumonji family H3K27 histone demethylase inhibitor |
SER | Sensitizer Enhancement Ratio |
ROS | Reactive oxygen species |