Table 3.
Statistical analysis and ratios of differential gene expression between groups.
| Comparison |
SMAD7 FC (PFDR) |
S1PR1 FC (PFDR) |
TNF FC (PFDR) |
SMAD2 FC (PFDR) |
SMAD3 FC (PFDR) |
SMAD4 FC (PFDR) |
|---|---|---|---|---|---|---|
| HD vs. RRMS rem | −2.29 (0.001) |
−1.28 (0.041) |
−1.19 (0.405) |
−1.28 (0.870) |
−1.17 (0.720) |
−1.12 (0.155) |
| HD vs. RRMS rel | −2.17 (0.001) |
−1.31 (0.010) |
−1.34 (0.123) |
−1.05 (0.372) |
−1.18 (0.130) |
−1.17 (0.110) |
| HD vs.CD rel | −4.65 (0.001) |
−1.59 (0.001) |
−2.25 (0.001) |
−1.40 (0.001) |
−1.64 (0.001) |
−1.60 (< 0.001) |
| RRMS rem vs. RRMS rel | 1.05 (1.000) |
−1.02 (1.000) |
−1.13 (0.690) |
1.02 (1.000) |
1.01 (1.000) |
−1.04 (1.738) |
| RRMS rem vs. CD rel | −2.02 (0.101) |
−1.24 (0.158) |
−1.89 (0.003) |
−1.3 (0.008) |
−1.40 (0.023) |
−1.43 (0.004) |
| RRMS rel vs. CD rel | −2.14 (0.046) |
−1.22 (0.137) |
−1.67 (0.006) |
−1.33 (0.006) |
−1.38 (0.016) |
−1.40 (0.006) |
HD, healthy donor; RRMS, remitting-recurrent multiple sclerosis; CD, Crohn’s disease; rel, relapsing; rem, remitting; PFDR, P value false discovery range.