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. 2020 Jan 8;22(2):80–88. doi: 10.1021/acscombsci.9b00199

Scheme 1. Reaction Conditions and Performance Summary of This Work versus Previously Reported Work.

Scheme 1

(i) Grubbs third generation catalyst A and its 2,2′-biphenyldiamine derivative B; (ii) previously reported conditions for the on-DNA RCM and CM reactions; (iii) our main conditions for the on-DNA RCM and CM reactions; *average percent conversion for the investigated substrate scope (22 substrates).