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Junctional current (Ij) and Vj sensitivity monitored in Xenopus oocyte pairs expressing Cx32 channels. A series of long (12 s, 30 s intervals) 100 mV Vj pulses progressively decrease peak and steady-state Ij by 50%–60% (τ = ~1.2 min). Ijpeak drops more dramatically, such that Ijss/Ijpeak increases from 0.4 to 0.6 (see inset). From Reference [115].
