Table 1. Demographic and clinical characteristics of the 238 tuberculin skin test-positive patients, according to access to prophylactic therapy with isoniazid.
| Access to prophylactic isoniazid | p-value | ||
|---|---|---|---|
|
| |||
| Yes N=210 | No N=28 | ||
| Male sex (%) | 147 (70.0) | 21 (75.0) | 0.585 |
| Age at TST (years) | 42 | 46 | 0.196 |
| Ethnicity (%) | |||
| White/Caucasian | 166 (79.0) | 25 (89.3) | |
| Non-white/caucasian | 40 (19.0) | 3 (10.7) | 0.434 |
| Not informed | 4 (1.9) | - | |
| Education (years) | |||
| 0 | 3 (1.4) | 0 | |
| ≤ 7 | 22 (10.5) | 2 (7.1) | |
| 8 - 11 | 134 (63.8) | 20 (71.4) | 0.864 |
| ≥ 12 | 29 (13.8) | 5 (17.9) | |
| Missing | 22 (10.5) | 1 (3.6) | |
| Under antiretroviral therapy (%) | 185 (88.1) | 26 (92.9) | 0.455 |
| CD4+ count at TST (cells/mm3) | 653 | 514 | 0.140 |
| Nadir CD4+ count (cells/mm3) | 215 | 153 | 0.031 |
| Undetectable HIV viral load (%) | 150 (71.4) | 23 (82.1) | 0.359 |
| Coexisting comorbidity (%) | 106 (50.5) | 12 (42.9) | 0.449 |
| Concurrent medications (%) | 110 (52.4) | 18 (64.3) | 0.235 |
| Tuberculin skin test ≥ 10 mm (%) | 150 (71.4) | 9 (32.1) | < 0.001 |
Numeric variables are presented as medians. Undetectable HIV viral load is defined as < 400 copies/mL.