A) (a) 2,4,5 triiodinated benzyl nucleus in commercial contrast media; (b)-(d) examples of iodinated vinylic monomers used for microsphere synthesis; and (e) 2,3,5, triiodinated compound for conjugation. B) (a) Schematics of microfluidics technique to fabricate alginate microspheres with in situ synthesized BaSO4 nanoparticles; (b) optical image of hydrated BaSO4/ALG microsphere and SEM image of a dried particle; and (c) BaSO4/ALG microsphere solution. C) Digital radiography of tantalum nanoparticle loaded calcium alginate particle (a-e) and blank calcium alginate particle (f-j) immediately, 1 week, 2 weeks, 3 weeks and 4 weeks of rabbit kidney after embolization. Figure components adapted and reproduced with permission.[193, 199, 202] Copyright 2016, Elsevier; 2015, American Chemical Society and 2018 Ivyspring International Publisher.