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. 2020 Feb 11;12:25. doi: 10.1186/s13148-020-0819-6

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Whole genome methylation profiling of ESCC and esophageal dysplasia samples. a Genome-wide methylation level of ESCC, dysplasia, and non-neoplastic samples. b Principal component analysis of whole genome bisulfite sequencing data