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. 2020 Jan 29;10(1):190285. doi: 10.1098/rsob.190285

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© 2020 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 2. — General model of neural crest development in a vertebrate embryo. Shown on the left is a cross-section of an open neural plate-stage embryo with neural plate (NP, CNS primordium) in the middle flanked bilaterally by the neural plate borders, which elevate as neural folds (NF) and ventrally by the notochord (N). The epidermal ectoderm (E), presumptive skin is shown extending ventral and lateral to the NPB. Shown on the right is a cross-section of the neural tube (NT) with premigratory neural crest cells (pMNCC) dorsally and migratory neural crest cells (MNCC) exiting this region. Dorsal is up and ventral is down.