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. 2020 Feb 12;20:130. doi: 10.1186/s12879-020-4852-z

Table 5.

Head-to-head comparison of different TB diagnostic tests, including Xpert Ultra and the MPT64 test among TB cases1

All TB cases
n = 31
MPT64 test performed Microscopy performed 1-step PCR performed Nested-PCR performed Culture performed
n = 31 n = 27 n = 18 n = 11 n = 26
MPT64 test + MPT64 test - Micro-scopy + Micro-scopy - 1-step PCR+ 1-step PCR- Nested-PCR+ Nested-PCR- Culture + Culture -
n = 10 n = 21 n = 6 n = 21 n = 6 n = 12 n = 7 n = 4 n = 16 n = 10
Microscopy + 2 4
Microscopy - 4 17
1-step PCR + 4 2 4 2
1-step PCR - 2 10 2 9
Nested-PCR + 5 2 1 3 1 0
Nested-PCR - 0 4 0 4 0 1
Culture + 3 13 4 12 5 7 2 2
Culture - 3 7 2 7 1 5 0 2
Xpert Ultra + 2 2 2 2 3 0 1 1 4 0
Xpert Ultra - 0 3 0 3 0 1 0 1 1 2

Abbreviations: TB, tuberculosis; PCR, polymerase chain reaction

1TB cases include both microbiologically confirmed TB cases (n = 26) and clinically diagnosed TB cases (n = 5)