Table 1.
Gene ontology annotated from over-expressed genes in spheroid cells compared with parental cells
| Term | Count | % | P-Value | Bonferroni |
|---|---|---|---|---|
| GO:0006351~transcription, DNA-templated | 96 | 18.3 | 2.99E-11 | 5.28E-08 |
| GO:0006355~regulation of transcription, DNA-templated | 73 | 13.9 | 2.40E-08 | 4.23E-05 |
| GO:0000122~negative regulation of transcription from RNA polymerase II promoter | 34 | 6.4 | 4.40E-04 | 0.540151 |
| GO:0045893~positive regulation of transcription, DNA-templated | 26 | 4.9 | 9.82E-04 | 0.82318 |
| GO:0006366~transcription from RNA polymerase II promoter | 25 | 4.7 | 0.001996 | 0.970526 |
| GO:0010467~gene expression | 6 | 1.1 | 0.006248 | 0.999984 |
| GO:0051726~regulation of cell cycle | 9 | 1.7 | 0.011435 | 1 |
| GO:0036498~IRE1-mediated unfolded protein response | 6 | 1.1 | 0.014689 | 1 |
| GO:0051569~regulation of histone H3-K4 methylation | 3 | 0.5 | 0.019287 | 1 |
| GO:0033762~response to glucagon | 3 | 0.5 | 0.023722 | 1 |