Table 4.
KEGG pathways annotated from under-expressed genes in spheroid cells compared with parental cells
| Term | Count | % | P-Value | Benjamini |
|---|---|---|---|---|
| hsa04510:Focal adhesion | 25 | 3.5 | 9.56E-07 | 2.44E-04 |
| hsa04810:Regulation of actin cytoskeleton | 23 | 3.2 | 1.58E-05 | 0.002008 |
| hsa04270:Vascular smooth muscle contraction | 16 | 2.2 | 3.63E-05 | 0.003084 |
| hsa05205:Proteoglycans in cancer | 21 | 2.9 | 7.53E-05 | 0.004789 |
| hsa04921:Oxytocin signaling pathway | 17 | 2.3 | 1.89E-04 | 0.009584 |
| hsa04520:Adherens junction | 11 | 1.5 | 3.41E-04 | 0.014382 |
| hsa04310:Wnt signaling pathway | 14 | 1.9 | 0.002365 | 0.082638 |
| hsa01100:Metabolic pathways | 64 | 8.9 | 0.00614 | 0.178252 |
| hsa00230:Purine metabolism | 15 | 2.1 | 0.00754 | 0.193017 |
| hsa04912:GnRH signaling pathway | 10 | 1.4 | 0.007892 | 0.182938 |