Fig. 1.

Functions of γδ T cells. γδ T cells differentiate into memory γδ T cells and function as immunosurveillance cells. Target cells were lysed by γδ T cell through granzyme-perforin, Fas–FasL, IFN-γ and TRAIL. γδ T cells can regulate Foxp3+ T-reg cell proliferation and secrete IL-10 and TGF-β during an immune response. γδ T cells can also differentiate into APCs and present antigens to αβ T cells. γδ T cells can activate, repress, or recruit other immunocytes during an immune response