Table 1.

CARRGO model parameters. All parameters are assumed to be non-negative except κ₂ which may be positive or negative.

parameter	description	unit
ρ	cancer cell net growth rate	day−1
K	carrying capacity	cell
κ1	CAR T-cell killing rate	day−1 cell−1
κ2	net rate of proliferation and exhaustion of CAR T-cells when stimulated by cancer cells	day−1 cell−1
θ	CAR T-cell death rate (persistence)	day−1