Table 2.
Top part: A, B and values obtained for each model (infinite cylinder model and 3D-cell simulations) when fitting the function A + B × cos (2ϕ). These values can be compared to the grey column on the left-hand side that indicates the average A, B and calculated over five metabolites (mean ± s.d.). Error on parameters extracted from geometric models (Dfree, dfiber) was estimated using Monte Carlo simulations. Models exhibiting embranchments exhibit lower values that better match our experimental data. Bottom part: Fitting to the infinite cylinders model for each 3D-cell simulation. This model fails to yield the expected ground truth values for Dfree and dfiber (i.e. 0.35 μm2/ms and 1 μm) for all simulations. Most strikingly, the obtained values are close to that of the average Dfree and dfiber obtained for our experimental data (mean ± s.d. over five metabolites), further illustrating the fact that the infinite cylinders model does not satisfactorily describe the experimental data.
