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. 2020 Jan 28;9(1):162–167. doi: 10.4103/jfmpc.jfmpc_903_19

Table 2.

Selected antibiotic with time administration and dose regimen for pre-intervention and post-intervention phases

Pre-intervention protocol
Drug Time of administration Dose regimen

Use of IV cefuroxime Before cord clamping 750 mg six doses every 8 h for 48 h
Use of metronidazole infusion Before cord clamping 500 mg six doses every 8 h for 48 h
Use of oral cefuroxime When discharged 500 mg every 12 h for 168 h (7 days)
Or use of oral amoxicillin-clavulanic acid When discharged 1,000 mg every 12 h for 168 h (7 days)
Use of oral metronidazole When discharged 500 mg every 8 h for 168 h (7 days)

Post-intervention protocol

Use of IV cefuroxime Before cord clamping 750 mg six doses every 8 h for 48 h
Use of oral cefuroxime When discharged 500 mg every 12 h for 168 h (7 days)