Table 2.
Comparison of Treatment Characteristics by Receipt of an Infectious Disease Consult
| Characteristic | ID consult (n=776) | No ID Consult (n=915) | P |
|---|---|---|---|
| Antifungal therapy (%) | |||
| Echinocandins | 328 (42.3) | 334 (36.5) | 0.11 |
| Azoles | 382 (49.2) | 412 (45.0) | 0.06 |
| Liposomal amphotericin B | 53 (6.8) | 41 (4.5) | 0.27 |
| No treatment | 13 (1.7) | 128 (14.0) | <0.001 |
| Physician unawareness | 8 (1) | 32 (3.5) | 0.007 |
| Considered a contaminant | 4 (0.5) | 89 (9.7) | 0.005 |
| Left against medical advice | 1 (0.1) | 7 (0.8) | 0.57 |
| Median treatment duration in days (IQR) | |||
| Total duration of therapy* | 18 (14, 35) | 14 (6, 20) | <0.001 |
| Echinocandins | 7 (2, 15) | 5 (2, 14) | 0.18 |
| Azoles | 13 (4, 18) | 10 (3, 15) | 0.004 |
| Liposomal amphotericin B | 4 (1, 8) | 3 (1.25, 5.75) | 0.47 |
| Microbiological follow-up | |||
| Number of blood cultures performed (median, IQR) | 9 (6, 15) | 7 (4, 12) | <0.001 |
| Number of positive blood cultures (median, IQR) | 2 (1, 3) | 1 (1, 2) | <0.001 |
| Median time to blood culture clearance (hrs., IQR) | 48 (27.5, 82) | 48 (23, 80) | 0.98 |
| Interventions | |||
| Echocardiography | |||
| Transthoracic | 414 (53.4) | 286 (31.3) | <0.001 |
| Transesophageal | 127 (16.4) | 44 (4.8) | <0.001 |
| Ophthalmology consult | 412 (53.1) | 160 (17.5) | <0.001 |
| Central line removal | 587 (75.6) | 538 (58.8) | <0.001 |
ID, infectious diseases. Categorical variables are presented as absolute number (percentage), continuous variables are presented as median (interquartile range).
*
Includes all antifungals agents used.