Table 3.
Pooled prevalence of VRE by subgroups
| Subgroups | Numbers of studies | No of enterococci isolates tested, N | Pooled prevalence of VRE, N (%) | 95% CI | I2 | P-value |
|---|---|---|---|---|---|---|
| Region | ||||||
| Addis Ababa | 7 | 56 | 13 (26.1) | 10.7–50.9 | 41.65 | 0.113 |
| Amhara | 8 | 568 | 38 (15.0) | 6.9–29.6 | 79.39 | < 0.001 |
| Oromia | 4 | 154 | 19 (9.0) | 2.8–25.7 | 71.49 | 0. 015 |
| SNNPR | 1 | 53 | 1 (1.9) | 0.8–19.8 | – | – |
| Study perioda | ||||||
| Before/in 2015 | 8 | 354 | 27 (16.5) | 6.5–31.5 | 81.09 | < 0.001 |
| After 2015 | 11 | 424 | 43 (16.3) | 7.6–31.3 | 69.20 | < 0.001 |
| AST method | ||||||
| Disc diffusion | 17 | 649 | 61 (16.9) | 9.3–28.9 | 66.89 | < 0.001 |
| Dilution/MIC | 3 | 182 | 10 (7.9) | 1.9–27.6 | 91.88 | < 0.001 |
| Type of specimen | ||||||
| Stool | 5 | 598 | 37 (5.9) | 2.8–11.7 | 0.00 | 0.629 |
| Urine | 4 | 26 | 10 (37.3) | 15.8–63.3 | 0.00 | 0.665 |
| Blood | 4 | 26 | 4 (22.0) | 6.9–51.9 | 45.06 | 0.141 |
| Wound swab | 1 | 2 | 1 (50.0) | – | – | – |
| Multi-siteb | 6 | 179 | 19 (16.8) | 8.0–31.9 | 77.87 | < 0.001 |
| Publication history | ||||||
| Published | 14 | 792 | 60 (11.3) | 6.4–19.2 | 72.86 | < 0.001 |
| Unpublished | 6 | 39 | 11 (31.9) | 12.9–59.7 | 25.82 | 0.241 |
a One study did not report its study period; b Studies used more than one type of specimen to isolate enterococci; MIC: Minimum Inhibitory Concentration