Table 4.
Pooled resistance profile of enterococcal isolates in Ethiopia
| Antibiotics | No of studies | No of enterococci isolates tested, N | Pooled resistance N, (%) | 95% CI | I2 (%) | P-value |
|---|---|---|---|---|---|---|
| Amoxicillin | 2 | 203 | 115 (56.5) | 49.6–63.2 | 0.00 | 0.382 |
| Amox-clavulanate | 2 | 225 | 71 (45.3) | 13.9–80.9 | 92.37 | < 0.001 |
| Ampicillin | 16 | 807 | 344 (44.5) | 29.2–61.0 | 90.83 | < 0.001 |
| Chloramphenicol | 12 | 777 | 188 (32.9) | 20.8–47.8 | 87.24 | < 0.001 |
| Ceftriaxone | 2 | 8 | 4 (50.0) | 20.0–80.0 | 0.00 | > 0.05 |
| Ciprofloxacin | 17 | 765 | 266 (36.5) | 27.0–47.3 | 75.30 | < 0.001 |
| Clindamycin | 4 | 224 | 59 (26.9) | 21.5–33.2 | 0.00 | 0.478 |
| Daptomycin | 2 | 29 | 0.5 (3.2)a | 0.5–19.7 | 0.00 | 0.974 |
| Doxycycline | 3 | 254 | 85 (55.1) | 22.2–84.0 | 90.21 | < 0.001 |
| Erythromycin | 14 | 780 | 374 (49.6) | 36.5–62.7 | 86.19 | < 0.001 |
| Gentamycin | 10 | 533 | 248 (37.7) | 22.2–56.1 | 88.86 | < 0.001 |
| Linezolid | 2 | 30 | 2 (9.9) | 2.8–29.0 | 0.00 | 0.336 |
| Nitrofurantoin | 9 | 404 | 117 (31.5) | 23.4–41.0 | 38.76 | 0.110 |
| Norfloxacin | 5 | 350 | 100 (39.9) | 18.6–66.6 | 90.21 | < 0.001 |
| Penicillin | 8 | 343 | 181 (60.7) | 39.9–78.3 | 86.63 | < 0.001 |
| Streptomycin | 3 | 179 | 74 (36.8) | 10.4–73.1 | 91.62 | < 0.001 |
| Tetracycline | 9 | 450 | 199 (53.7) | 35.8–70.7 | 86.95 | < 0.001 |
| SXT | 10 | 241 | 104 (39.1) | 21.48–59.6 | 45.58 | 0.088 |
| MDR - enterococci | 20 | 825 | 543 (60.0) | 42.9–75.0 | 90.27 | < 0.001 |
SXT Trimethoprim-Sulfamethoxazole, MDR Multidrug resistance
a Continuity correction (0.5) is added to the study