Table 6.
Meta-analysis of TNF-α 1031 T/C polymorphisms and CAD susceptibility
| Genetic Model | N (case/control) | OR(95%CI) | P* | I2 | P# | P value | |
|---|---|---|---|---|---|---|---|
| Begg | Egger | ||||||
| CC vs TT + CT | 3781/3845 | 1.020 (0.677,1.539) | 0.013 | 58.6% | 0.923 | 0.602 | 0.458 |
| CC + CT vs TT | 3781/3845 | 0.945 (0.860,1.039) | 0.476 | 0.0% | 0.243 | 0.466 | 0.786 |
| CC vs TT | 3781/3845 | 0.999 (0.666,1.498) | 0.018 | 56.5% | 0.997 | 0.602 | 0.465 |
| CT vs TT | 3781/3845 | 0.929 (0.842,1.025) | 0.401 | 4.1% | 0.141 | 0.175 | 0.951 |
| C vs T | 3781/3845 | 0.973 (0.898,1.054) | 0.248 | 21.9% | 0.505 | 1.000 | 0.624 |
*P value of Heterogeneity chi-squared
#P value of Pooled statistic