Figure 2. Pathway over-representation analysis derived from plasma metabolomics.
A. Pathways overrepresented in premutation vs. controls were obtained by utilizing the Metabolite Set Enrichment Analysis (MSEA). B. Metabolites were analyzed using the Pathway Analysis module of MetaboAnalyst, which combines results from the pathway enrichment analysis with the pathway topology analysis to identify the most relevant pathways in the premutation. The table includes the data with p ≤ 0.27 associated with the pathway impact plot.