Table 1:
Baseline characteristics and comorbidities in bicuspid aortic valve stenosis patients who underwent either surgical or transcatheter aortic valve replacement
| Variable | SAVR (N = 36,629) | TAVR (N = 423) | P value |
|---|---|---|---|
| Age | 56.7 ± 14.7 | 65.9 ± 15.1 | <0.001 |
| Sex | |||
| Female | 26.3 | 34.3 | <0.001 |
| Race | 0.027 | ||
| White | 85.3 | 89.2 | |
| Black | 2.1 | 2.4 | |
| Hispanic | 5.9 | 4.8 | |
| Asian or Pacific Islander | 1.4 | 2.4 | |
| Native American | 0.4 | 0.0 | |
| Other | 3.6 | 1.2 | |
| Elective hospitalization | 78.8 | 79.6 | 0.112 |
| Primary expected payer | <0.001 | ||
| Medicare | 31.1 | 31.4 | |
| Medicaid | 6.8 | 6.8 | |
| Private insurance | 55.6 | 55.4 | |
| Self-pay | 2.9 | 2.9 | |
| No charge | 0.4 | 0.4 | |
| Other | 3.2 | 3.1 | |
| Median household income (percentile) | <0.001 | ||
| 0–25 | 19.0 | 19.1 | |
| 26–50 | 24.6 | 24.5 | |
| 51–75 | 27.3 | 27.3 | |
| 76–100 | 29.1 | 29.1 | |
| Bed size | <0.001 | ||
| Small | 7.4 | 2.4 | |
| Medium | 19.0 | 14.2 | |
| Large | 73.6 | 83.5 | |
| Location/teaching status | 0.001 | ||
| Rural | 1.7 | 0.0 | |
| Urban nonteaching | 18.7 | 10.4 | |
| Urban teaching | 79.6 | 89.6 | |
| Hospital region | 0.114 | ||
| Northeast | 21.8 | 22.2 | |
| Midwest | 26.2 | 23.1 | |
| South | 31.5 | 33.1 | |
| West | 20.5 | 23.4 | |
| Carotid artery disease | 2.4 | 3.5 | 0.153 |
| Coronary artery disease | 32.6 | 42.3 | <0.001 |
| Smoking | 12.9 | 7.1 | <0.001 |
| Hyperlipidemia | 48.9 | 55.5 | 0.008 |
| Prior stroke | 4.9 | 8.1 | 0.003 |
| Atrial fibrillation | 33.5 | 35.3 | 0.469 |
| Alcohol abuse | 3.6 | 3.5 | 1.000 |
| Deficiency anemia | 13 | 15.4 | 0.165 |
| RA/collagen vascular disease | 1.9 | 5.9 | <0.001 |
| Chronic blood loss anemia | 0.9 | 2.4 | 0.008 |
| Congestive heart failure | 0.9 | 15.4 | <0.001 |
| Chronic lung disease | 16.7 | 16.7 | <0.001 |
| Coagulopathy | 28.1 | 23.6 | 0.045 |
| Depression | 7.9 | 10.6 | 0.043 |
| Obesity | 17.5 | 9.5 | <0.001 |
| Weight loss | 2.8 | 8.3 | <0.001 |
| Uncomplicated DM | 14.9 | 17.7 | 0.112 |
| Complicated DM | 2.4 | 7.1 | <0.001 |
| Drug abuse | 0.0 | 2.1 | <0.001 |
| Hypertension | 61.3 | 70.7 | <0.001 |
| Hypothyroidism | 8.5 | 8.5 | 0.111 |
| Liver disease | 1.8 | 1.8 | <0.001 |
| Lymphoma | 0.4 | 0.0 | 0.417 |
| Fluid and Electrolyte disorders | 33.9 | 33.8 | 0.003 |
| Other neurological disorders | 3.9 | 3.9 | 0.377 |
| Paralysis | 0.9 | 1.0 | 0.008 |
| PVD | 30.4 | 30.3 | <0.001 |
| Renal failure | 6.6 | 6.8 | <0.001 |
| Pulmonary circulation disorders | 0.4 | 0.4 | <0.001 |
| Psychosis | 2.1 | 2.1 | 0.056 |
PCI = percutaneous coronary intervention;
CABG = coronary artery bypass graft; RA = Rheumatoid arthritis; DM = diabetes; PVD = peripheral vascular disease.