Table 1.
Characteristics | All patients (n=100) | Normal ABI group (n=82) | Low ABI group (n=18) | P |
---|---|---|---|---|
Age (years) | 64.80±13.66 | 63.39±14.03 | 71.22±9.79 | 0.027* |
HD duration (months) | 83.93±68.31 | 82.83±68.34 | 88.93±69.89 | 0.733 |
Height (cm) | 157.65±8.65 | 157.41±9.01 | 158.72±7.02 | 0.565 |
Pre-HD body weight (kg) | 59.60±13.36 | 58.49±13.10 | 64.63±13.79 | 0.078 |
Post-HD body weight (kg) | 57.47±13.03 | 56.34±12.73 | 62.62±13.51 | 0.064 |
Waist circumference (cm) | 88.49±12.21 | 87.48±11.91 | 93.11±12.82 | 0.076 |
BMI (kg/m2) | 23.08±4.80 | 22.68±4.60 | 24.92±5.37 | 0.073 |
Body fat mass (%) | 26.82±7.64 | 26.44±7.49 | 28.57±8.28 | 0.286 |
Left-ABI | 1.04±0.19 | 1.11±0.15 | 0.77±0.12 | <0.001* |
Right-ABI | 1.02±0.16 | 1.06±0.13 | 0.86±0.19 | <0.001* |
SBP (mmHg) | 143.32±26.54 | 144.47±27.23 | 138.06±23.04 | 0.355 |
Diastolic blood pressure (mmHg) | 77.29±17.22 | 77.84±17.63 | 74.78±15.39 | 0.497 |
Total cholesterol (mg/dL) | 143.84±32.70 | 147.18±34.15 | 133.17±22.87 | 0.127 |
Triglyceride (mg/dL) | 109.50 (75.75-173.25) | 107.00 (72.50-169.75) | 116.00 (94.50-180.50) | 0.412 |
Glucose (mg/dL) | 128.50 (107.75-160.75) | 128.50 (110.00-151.00) | 129.00 (104.00-233.50) | 0.612 |
Albumin (mg/dL) | 4.12±0.47 | 4.16±0.50 | 3.94±0.26 | 0.068 |
Globulin (mg/dL) | 3.17±0.60 | 3.20±0.63 | 3.04±0.46 | 0.334 |
Blood urea nitrogen (mg/dL) | 62.65±14.93 | 63.57±14.60 | 58.44±16.08 | 0.188 |
Creatinine (mg/dL) | 9.02±2.01 | 9.19±2.14 | 8.27±1.03 | 0.079 |
Total calcium (mg/dL) | 8.98±0.74 | 8.98±0.77 | 8.99±0.59 | 0.939 |
Phosphorus (mg/dL) | 4.70±1.28 | 4.69±1.31 | 4.74±1.17 | 0.884 |
iPTH (pg/mL) | 195.90 (57.28-373.78) | 227.25 (66.78-497.13) | 152.45 (28.90-219.70) | 0.060 |
Adiponectin (µg/mL) | 45.79±10.41 | 47.20±9.45 | 39.36±12.35 | 0.003* |
Urea reduction rate | 0.74±0.04 | 0.74±0.04 | 0.73±0.04 | 0.196 |
Kt/V (Gotch) | 1.36±0.17 | 1.37±0.17 | 1.32±0.16 | 0.203 |
Female, n (%) | 55 (55.0) | 47 (57.3) | 8 (44.4) | 0.320 |
DM, n (%) | 35 (35.0) | 25 (30.5) | 10 (55.6) | 0.043* |
Hypertension, n (%) | 52 (52.0) | 44 (53.7) | 8 (44.4) | 0.479 |
Current smoking | 11 (11.0) | 8 (9.8) | 3 (16.7) | 0.396 |
ACE inhibitor or ARB use, n (%) | 25 (25.0) | 22 (26.8) | 3 (16.7) | 0.367 |
β-blocker, n (%) | 29 (29.0) | 26 (31.7) | 3 (16.7) | 0.203 |
CCB, n (%) | 39 (39.0) | 34 (41.5) | 5 (27.8) | 0.281 |
Statin, n (%) | 18 (18.0) | 14 (17.1) | 4 (22.2) | 0.607 |
Fibrate, n (%) | 12 (12.0) | 9 (11.0) | 3 (16.7) | 0.501 |
*P<0.05 was considered statistically significant. Values for continuous variables given as means±SD and test by student’s t-test, variables not normally distributed given as medians and interquartile range and test by Mann-Whitney U-test, Data are expressed as number of patients and analysis was done using the Chi-square test. ABI: Ankle brachial indices, HD: Hemodialysis, Kt/V: Fractional clearance index for urea, ACE: Angiotensin-converting enzyme, ARB: Angiotensin-receptor blocker, CCB: Calcium-channel blocker, SD: Standard deviation, BMI: Body mass index, SBP: Systolic blood pressure, iPTH: Intact parathyroid hormone, DM: Diabetes mellitus