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. 2020 Jan 8;45(3):703–714. doi: 10.3892/ijmm.2020.4459

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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IGF2 promotes OC cell proliferation, migration, invasion and drug resistance. A2780 overexpressing or with silenced IGF2 were prepared. (A) EdU labeling (magnification, ×200) and (B) EdU-positive cell rate. (C) Cell migration and invasion images (magnification, ×200) and abilities. (D) Cell survival rates at different cisplatin concentrations. Data are expressed as the mean ± standard error; each experiment was repeated three times. ^*P<0.05 vs. pcDNA-NC; ^#P<0.05 vs. si-NC. PLAG1, pleomorphic adenoma gene 1; IGF2, insulin-like growth factor-2; si, small interfering RNA; NC, negative control; OC, ovarian cancer.