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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Trends Neurosci. 2020 Jan 15;43(2):88–102. doi: 10.1016/j.tins.2019.12.003

Figure 5.

Figure 5.

Prestin in the chicken cochlea. (A) Images of hair bundles (top), middle of tectorial membrane (middle) and top of tectorial membrane showing 3μm glass beads (bottom). (B). Schematic of experiment to polarize hair cells with electrodes on either side of chicken basilar papilla. (C). Displacements evoked by 100 μA extracellular current pulse: intracellular voltage record from tall hair cell, deflections of hair bundle and of bead, both towards neural limb. (D). Labeling of short hair cells with prestin antibody shows more at the basal than apical regions of papilla. (E) Na salicylate inhibits hair bundle motion to 100 μA current pulse across papilla. (F) Motion of hair bundle is graded with depolarization of voltage-clamped short hair cell.