Table 2.

Univariable and multivariable Cox-hazard analysis in patients without FSGS recurrence compared with patients with FSGS recurrence

Predictors	Missing Values, n (%)	Univariable Analysis	Univariable Analysis	Multivariable Analysis	Multivariable Analysis	Model Selection
		HR (95% CI)	P Value	HR (95% CI)	P Value	HR (95% CI), P Value
Geographic location of center
United States	0 (0)	Ref		Ref		Ref
Brazil	0 (0)	1.42 (0.77–2.62)	0.27	0.45 (0.21 to 0.98)	0.05	0.46 (0.24 to 0.90), 0.02
Europe	0 (0)	1.11 (0.57 to 2.17)	0.74	0.39 (0.18 to 0.87)	0.02	0.39 (0.19 to 0.79), 0.009
Age at diagnosis FSGS, per 10 yr	4 (2)	1.14 (0.96 to 1.37)	0.12	1.37 (1.12 to 1.68)	0.002	1.31 (1.09 to 1.56), 0.003
White race	19 (11)a	1.80 (0.95 to 3.41)	0.07	2.39 (1.16 to 4.96)	0.02	2.14 (1.08 to 4.22), 0.03
BMI, per 1 kg/m2	1 (1)	0.94 (0.89 to 0.99)	0.03	0.89 (0.83 to 0.96)	0.002	0.89 (0.83 to 0.95), 0.001
Time on dialysis, per mo (log)	2 (1)	1.04 (0.86 to 1.27)	0.69	1.10 (0.85 to 1.42)	0.49	NS
Native nephrectomy	1 (1)	2.56 (1.21 to 5.41)	0.01	2.89 (1.09 to 7.66)	0.03	2.76 (1.16 to 6.57), 0.02
Living donor	0 (0)	1.23 (0.72 to 2.11)	0.45	1.55 (0.76 to 3.16)	0.23	NS
Age donor, per 10 yr	14 (8)	0.99 (0.82 to 1.19)	0.90	0.84 (0.66 to 1.06)	0.14	NS
HLA mismatch >3	10 (6)	0.65 (0.37 to 1.14)	0.14	0.71 (0.39 to 1.31)	0.27	NS
Presence of DSA	15 (9)	0.98 (0.35 to 2.72)	0.97	0.83 (0.25 to 2.79)	0.76	NS
Use of induction	3 (2)	1.12 (0.51 to 2.47)	0.79	1.23 (0.53 to 2.89)	0.63	NS
Plasmapheresis pretransplant	0 (0)	1.28 (0.63 to 2.61)	0.50	1.27 (0.54 to 2.97)	0.58	NS
Immunosuppression with tacrolimus + MMF + steroids	1 (1)	1.01 (0.57 to 1.81)	0.96	0.88 (0.46 to 1.66)	0.69	NS
Time to ESKD, per mo	40 (23)	1.00 (0.99 to 1.00)	0.26

HR, hazard ratio; 95% CI, 95% confidence interval; Ref, reference; BMI, body mass index; NS, not significant; DSA, donor-specific antibody; MMF, mycophenolate mofetil.

^aMost patients with missing race come from France, where race/ethnicity is not allowed to be reported.