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. Author manuscript; available in PMC: 2020 Feb 12.
Published in final edited form as: Immunol Rev. 2019 Jan;287(1):226–235. doi: 10.1111/imr.12724

FIGURE 3.

FIGURE 3

Severe periodontitis in leukocyte adhesion deficiency I. (A) Panoramic oral radiograph of a 15-year-old male with LAD-I. Patient has lost the majority of his teeth due to severe periodontitis. The remaining dentition presents with severe bone loss. Dotted white lines indicate the physiologic level of bone and dotted blue lines demonstrate bone levels in this clinical case. (B) Hematoxylin and eosin (H&E) staining of extracted tooth from a LAD-I patient. Soft tissue surrounding the entire tooth is indicative of complete destruction of tooth supporting bone. Diffused inflammatory infiltrate is observed in all surrounding mucosal tissues