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. 2020 Feb;41(2):310–317. doi: 10.3174/ajnr.A6374

Comparison of histologically identified plaque components in hyper- and hypointense areas on QSM imagesa

Plaque Components Hyperintense Area (n = 26) Hypointense Area (n = 9) P Value
Intraplaque hemorrhage 19 (73) 0 (0) .0002
Iron deposition 20 (76.9) 0 (0) <.0001
Calcification 7 (26.9) 8 (88.9) .002
Fibrous matrix deposits 9 (34.6) 9 (100) .001
Dense inflammatory infiltrates 10 (38.5) 4 (44.4) 1.0
Necrotic core without intraplaque hemorrhage 5 (19.2) 1 (11.1) 1.0
a

Data in parentheses are percentages.