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Venn diagram of predicted secreted proteins by classical or alternative route in Paracoccidioides species. (A) P. lutzii, (B) P. americana, (C) P. brasiliensis, (D) P. restrepiensis. Numerical values represented by the number of exoantigens identified. SigP: (SignalP 4.1) prediction of secretion by classical route. SecP: (SecretomeP 2.0) prediction of secretion by alternative routes. None: proteins that have no prediction for secretion in the used algorithms.
