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. 2020 Jan 28;10:2968. doi: 10.3389/fmicb.2019.02968

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Copyright © 2020 Moreira, Oliveira, Silva, Inácio, Bailão, Parente-Rocha, Cruz-Leite, Paccez, de Almeida Soares, Weber and Borges.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of the three-dimensional (3-D) model of the exoantigens of Paracoccidioides species by I-TASSER. The models were generated using the structure of the exoantigens identified during the immunoproteomics that presented non-homologous epitopes to other pathogenic organisms. The 3-D representation of predicted non-homologous epitopes was performed after structural refinement and energy minimization using ModRefiner and GalaxyWEB software. 3-D view of the non-homologous and hydrophilic epitopes predicted in (A) P. lutzii, (B) P. americana, (C) P. brasiliensis, and (D) P. venezuelensis.