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. 2019 Nov 13;11(1):120–134. doi: 10.1002/jcsm.12497

Figure 4.

Figure 4

Vitamin D repletion modulates expression of key molecules implicated in adipose tissue browning in Ctns−/− mice. Gene expression and protein content of Cox2 signalling pathway (Cox2 and Pgf2α) and Tlr/NF‐κB pathway (Tlr2, MyD88, and Traf6 as well as relative NF‐κB phosphorylated Ser337 p50/total p50 ratio, relative NF‐κB phosphorylated Ser536 p65/total p65 ratio, and Iκκ‐α phosphorylated Thr23) in inguinal white adipose tissue were measured. For relative NF‐κB phosphorylated Ser337 p50/total p50 ratio and relative NF‐κB phosphorylated Ser536 p65/total p65 ratio in mice, value was normalized with respect to wild‐type (WT) control mice. Final results were expressed in arbitrary units, with one unit being the mean level in WT control mice. Results are analysed and expressed as in Figure 1.