Table 2.
Controls | PD-OFF |
PD-ON |
pvaluea | pvalueb | pvaluec | AUC | CC, % | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
mean± SD | reliability | UPDRS correlation | mean± SD | reliability | UPDRS correlation | |||||||
Two-target test | ||||||||||||
Total taps | 101±32 | 55±27 | 0.96 | −0.55 | 84±20 | 0.85 | −0.53 | 0.002 | 0.15 | 0.004 | 0.82 | 73 |
Tap interval, ms | 324±93 | 708±413 | 0.92 | 0.51 | 375±97 | 0.75 | 0.41 | 0.01 | 0.22 | 0.01 | 0.80 | 77 |
Tap duration, ms | 113±120 | 74±65 | 0.88 | 0.35 | 108±158 | 0.95 | −0.40 | 0.36 | 0.94 | 0.55 | 0.60 | 46 |
Tap accuracy, pixels | 1,515±646 | 1,112±901 | 0.77 | −0.51 | 2,008±996 | 0.90 | −0.46 | 0.24 | 0.18 | 0.006 | 0.78 | 73 |
Pronation-supination test | ||||||||||||
Total taps | 84±21 | 55±21 | 0.60 | −0.31 | 78±20 | 0.83 | −0.55 | 0.006 | 0.54 | 0.003 | 0.77 | 68 |
Tap interval, ms | 377±92 | 650±387 | 0.81 | 0.27 | 409±112 | 0.76 | 0.42 | 0.04 | 0.50 | 0.03 | 0.75 | 64 |
Tap duration, ms | 4±2 | 3±1 | 0.06 | 0.10 | 3±2 | 0.88 | 0.20 | 0.26 | 0.89 | 0.46 | 0.45 | 50 |
Data are reported as the mean± SD unless specified otherwise. Data were collected for most affected side and dominant hand forp and controls, respectively. PD-OFF/ON, Parkinson disease patients in the OFF state (reemergence of parkinsonian deficits)/ON state (maximal dopaminergic medication efficacy); UPDRS, Movement Disorder Society-Unified Parkinson's Disease Rating Scale; AUC, area under the curve for PD-OFF vs. PD-ON; CC, correct classification.
Unpaired/Satterthwaitet test between controls and PD-OFF.
Unpaired/Satterthwaitet test between controls and PD-ON.
Pairedt test between PD-OFF and PD-ON.